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张强锋

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张强锋

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Email:?qczhang(at)tsinghua(dot)edu(dot)cn

主页:http://zhanglab.life.tsinghua.edu.cn


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代表性科研论文:

[1].? L Sun*, FM Fazal*, P Li*, JP Broughton, B Lee, L Tang, W Huang, HY Chang#, QC Zhang# (2019) RNA structure maps across mammalian cellular compartments. Nat Struct Mol Biol. 26(4):322-330.

[2]?? P Li*, Y Wei*, M Mei*, L Tang*, L Sun, W Huang, J Zhou, C Zou, S Zhang, CF Qin, T Jiang, J Dai, X Tan#, QC Zhang#. (2018) Integrative Analysis of Zika Virus Genome RNA Structure Reveals Critical Determinants of Viral Infectivity. Cell host & microbe 24(6): 875-886.

[3].? X Qian*, J Zhao*, PY Yeung*, QC Zhang#, CK Kwok#. (2018) Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches. Trends in biochemical sciences 44(1): 33-52. (review)

[4]?? Gong J*, Shao D*, Xu K, Lu Z, Lu ZJ, Yang YT, Zhang QC#. (2018) RISE: a database of RNA interactome from sequencing experiments. Nucleic Acids Res., 46(D1): D194-D201.

[5].? Lu Z*, Zhang QC*, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech, TR, Chang HY. (2016) RNA duplex map in living cells reveals higher order transcriptome structure. Cell, 165 (5), 1267-1279.

[6].? Quinn JJ*, Zhang QC*, Georgiev P, Ilik IA, Akhtar A, Chang HY. (2016) Rapid evolutionary turnover underlies conserved lncRNA–genome interactions. Genes & Development, 30 (2), 191-207.

[7].? Flynn RA*, Zhang QC*, Spitale RC, Lee B, Mumbach MR, and Chang HY. (2016) Transcriptome-wide interrogation of RNA secondary structure in living cells with icSHAPE. Nature Protocols, 11 (2), 273-290.

[8].? Spitale R*, Flynn RA*, Zhang QC*, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, and Chang HY. (2015) Structural imprints in vivo decode RNA regulatory mechanisms. Nature, 519: 486-90.

[9].? Chu C, Zhang QC, Texira S, Bharadwaj M, Calabrese M, Magnuson T, Heard H and Chang HY. (2015) Developmentally regulated and modular assembly of Xist RNA binding proteins coordinate chromatin silencing. Cell 161 (2), 404-416.

[10]. Wan Y*, Qu K*, Zhang QC, Manor O, Ouyang Z, Zhang J, Snyder MP, Segal E and Chang HY. (2014) Landscape and variation of RNA secondary structure across the human transcriptome. Nature, 505(7485), 706-709.

[11]. Zhang QC, Petrey D, Garzon J, Deng L, and Honig B. (2013) PrePPI: A structure-informed database of protein-protein interactions. Nucleic Acids Research, 41:D828-33.

[12]. Zhang QC*, Petrey D*, Deng L, Qiang L, Shi Y, Chan AT, Bisikirska B, Lefebvre C, Accili D, Hunter T, Maniatis T, Califano A, and Honig B. (2012) Structure-based prediction of protein-protein interactions on a genome-wide scale. Nature, 490: 556-60.

[13]. Zhang QC*, Deng L*, Guan J, Honig B and Petrey D. (2011) PredUs: a web server for predicting protein interfaces using structural neighbors. Nucleic Acids Res., 39: W283-87.

[14]. Zhang QC, Petrey D, Norel R, and Honig B, Protein interface conservation across structural space. (2010) Proceedings of the National Academy of Sciences, 107(24): 10896-109.

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